Use: Bathocuproine is a Cu(I)-specific
colorimetric reagent. An orange Bathocuproine-Cu(I)
complex can be extracted with n-hexylalcohol or
iso-amylalcohol.
The maximum wavelength of the complex extract is 479
nm. The Cu(I) detection range is 0.1-10 ppm.
Bathocuproine has been used to determine trace
amounts of Cu(I) in wine and purified tellurium
samples. Bathocuproine is soluble in organic
solvents such as nitrobenzene and insoluble in
water.
Two new reagents, neocuproine and bathocuproine are
proposed for simple, sensitive and selective
spectrophotometric methods for the determination of
dibenzazepine class of drugs. In the proposed method
copper (II) reacts with imipramine hydrochloride,
desipramine hydrochloride, clomipramine
hydrochloride, trimipramine maleate and opipramol
and subsequently with neocuproine or bathocuproine
in an acetic acid medium to yield yellow or
orange-red colour, with maximum absorption at 460 or
480 nm, respectively. A reaction mechanism is
proposed with drug -metal and reagent ratio of 1:2.
